Literatuur

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1) Radjabzadeh, D., Bosch, J.A., Uitterlinden, A.G. et al. Gut microbiome-wide association study of depressive symptomsNat Commun 13, 7128, 2022.  
2) Steenbergen, L., Sellaro, R., Van Hemert, S., et al. A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood, Brain, Behavior, and Immunity, Volume 48, 2015, Pages 258-264, ISSN 0889-1591.  
3) Sanada K, Nakajima S, Kurokawa S, et al. Gut microbiota and major depressive disorder: A systematic review and meta-analysis.J Affect Disord. 2020 Apr 1;266:1-13. Epub 2020 Jan 23. PMID: 32056863. 
 4) Mayer, E.A., Nance, K., Chen, S., The Gut-Brain Axis. Annu Rev Med. 2022 Jan 27;73:439-453. Epub 2021 Oct 20. PMID: 34669431. 
 5) Messaoudi, M., Violle, N., Bisson, J.F., et al. Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers, Gut Microbes, 2:4, 256-261, 2011. 
 6) Kato-Kataoka, A., Nishida, K., Takada, M., et al.Fermented milk containing Lactobacillus casei strain Shirota prevents the onset of physical symptoms in medical students under academic examination stress. Benef Microbes. 2016;7(2):153-6. Epub 2015 Dec 21. PMID: 26689231. 
 7) Salleh, R.M., Kuan, G., Aziz, M.N.A., et al. Effects of Probiotics on Anxiety, Stress, Mood and Fitness of Badminton Players. Nutrients. 2021 May 24;13(6):1783. PMID: 34073684; PMCID: PMC8225117. 
 8) Mörkl, S., Butler, M.I., Holl, A., Probiotics and the Microbiota-Gut-Brain Axis: Focus on Psychiatry. Curr Nutr Rep. 2020 Sep;9(3):171-182. Erratum in: Curr Nutr Rep. 2020 Jun 5; PMID: 32406013; PMCID: PMC7398953. 
9) Otaka M, Kikuchi-Hayakawa H, Ogura J, et al., Effect of Lacticaseibacillus paracasei Strain Shirota on Improvement in Depressive Symptoms, and Its Association with Abundance of Actinobacteria in Gut Microbiota. Microorganisms. 2021 May 10;9(5):1026. PMID: 34068832. 

1) McFarland LV. Epidemiology, risk factors and treatments for antibiotic-associated diarrhea. Dig Dis. 1998 Sep-Oct;16(5):292-307 
2) Agamennone et al. BMC A practical guide for probiotics applied to the case of antibiotic-associated diarrhea in The Netherlands, Gastroenterology. 2018; 18:103. 
3) McFarland LV. Emerging therapies for Clostridium difficile infections. Expert Opin Emerging Drugs; 2011. 16 (3): 425-439. 
4) Claassen E. Cost-benefi t relation of diet and probiotics in iatrogenic bowel irregularity (IBI). Frontiers in Pharmacology. 2014;5:14. 
5) Videlock E.J., Cremonini F. Meta-analysis: probiotics in antibiotic-associated diarrhoea. Aliment Pharmacol Ther. 2012; 35: 1355-1369. 
6) Hempel, S. et al. Probiotics for the Prevention and Treatment of Antibiotic-Associated Diarrhea, A Systematic Review and Meta-analysis. JAMA. 2012;307(18):1959-1969. 
7) Goldenberg JZ. et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database Syst Rev. 2017;12(12):CD006095.  
8) Szajewska H. et al. Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Children. J Pediatr Gastroenterol Nutr. 2016;62(3):495-506.   
9) Wong S. et alLactobacillus casei Shirota probiotic drink reduces antibiotic-associated diarrhoea in patients with spinal cord injuries: a randomised controlled trial. Br J Nutr. 2014 ; 111 (4): 672-8 
10) Pirker A. et al. Effects of antibiotic therapy on the gastrointestinal microbiota and the infl uence of Lactobacillus casei. Food and Agricultural Immunology 2013;24(3):315-330 
11) Stockenhuber, A. et alPreventing Antibiotic Associated Diarrhoea using a Probiotic Lactobacillus casei Preparation. Gut 2008; 57 (Suppl II) A20
12) Lee L. et al. Prevention of relapse following Clostridium difficile infection using probiotic Lactobacillus casei Shirota. International Journal of Probiotics & Prebiotics. 2013; 8(4):145-148.
13) Flach J, et al. The underexposed role of food matrices in probiotic products: Reviewing the relationship between carrier matrices and product parameters. Crit Rev Food Sci Nutr. 2018;58(15):2570-2584.  
14) Ouwehand A. et al. Effectiveness of Multi-strain Versus Single-strain Probiotics: Current Status and Recommendations for the Future, J Clin Gastroenterol. 52():S35–S40, NOV 2018 
15) Lee B. et al Attenuation of colitis by Lactobacillus casei BL23 is dependent on the dairy delivery matrix. Appl Environ Microbiol. 2015;81(18):6425-35.  
16) Burgain J. Encapsulation of Lactobacillus rhamnosus GG in microparticles: Influence of casein to whey protein ratio on bacterial survival during digestion. Innovative Food Science & Emerging Technologies. 2013. 19: 233–242 
17) Agamennone V. et al. Een praktische gids voor probiotica ter preventie van antibiotica-gerelateerde diarree in Nederland. Nederlands Platform voor Farmaceutisch Onderzoek. 2019;4:a1689 
18) Guo Q, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database of Systematic Rev. 2019; 4(4): CD004827. 
19) Former, M. Probiotica als aanvullende therapie bij antibioticum geassocieerde diarree, Voeding en Visie, 2001. 24. 2: 6-7. 
20) Hickson M. et al. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial. BMJ 2007 ;335(7610):80 
21) ISAPP Probiotic Guide

1) Claesson M.J. et alGut microbiota composition correlates with diet and health in the elderly.  Nature. 2012 Aug 9;488(7410):178-84. 
2) Eldermet-project, University College Cork, Cork University Hospital, and Teagasc, Moorepark
3) Ragonnaud, E., Biragyn, A. Gut microbiota as the key controllers of “healthy” aging of elderly people. Immun Ageing. 2021;18:2. 
4) Roswall J, et al. Developmental trajectory of the healthy human gut microbiota during the first 5 years of life. Cell Host Microbe. 2021 May 12;29(5):765-776. 
5) Duncan S.H., Flint H.J. Probiotics and prebiotics and health in ageing populations. Maturitas. 2013 May;75(1):44-50. 
6) Tiihonen, K. et al. Human intestinal microbiota and healthy ageing. Ageing Res Rev. 2010 Apr; 9(2):107-16. 
7) Berg, S. van den, et al. Voeding in relatie tot aandoeningen en medicijngebruik bij ouderen. Rijksinstituut voor Volksgezondheid en Milieu. 2012; RIVM Rapport 350047001. 
8) Cevenini, E. et al. Inflamm-ageing. Curr Opin Clin Nutr Metab Care. 2013 Jan;16(1):14-20. 
9) Bouterse, M. et alHuisartsenzorg in cijfers, Obstipatie, Huisarts en Wetenschap. 2010; 9:463-463 
10) Flach, J. et al. Economic Potential of Probiotic Supplementation in Institutionalized Elderly with Chronic Constipation. PharmaNutrition. 2018. 6. 10.1016 

1. Berg, S. van den, et al. Voeding in relatie tot aandoeningen en medicijngebruik bij ouderen. Rijksinstituut voor Volksgezondheid en Milieu. 2012; RIVM Rapport 350047001.
2. Bouterse, M. et al. Huisartsenzorg in cijfers, Obstipatie, Huisarts en Wetenschap. 2010; 9:463-463
3. Claesson M.J. et al. Gut microbiota composition correlates with diet and health in the elderly. Nature. 2012 Aug 9; 488(7410):178-84
4. Flach, J. et al. Economic Potential of Probiotic Supplementation in Institutionalized Elderly with Chronic Constipation. PharmaNutrition. 2018. 6. 10.1016
5. Duncan S.H., Flint H.J. Probiotics and prebiotics and health in ageing populations. Maturitas. 2013 May;75(1):44-50.
6.Ocke M. et al. Diet of community-dwelling older adults : Dutch National Food Consumption Survey Older adults 2010-2012. Rijksinstituut voor Volksgezondheid en Milieu. RIVM Rapport 050413001.
7. Chmielewska, A., Szajewska, H. Systematic review of randomised controlled trials: Probiotics for functional constipation, World J Gastroenterol, 2010, January 7; 16(1): 69–75
8. Nieuwboer, M. van den, et al. Improving the bowel habits of elderly residents in a nursing home using probiotic fermented milk. Beneficial Microbes. 2015; Feb 17:1-8.
9. Frazzitta, Giuseppe et al. Severe Constipation in Parkinson’s Disease and in Parkinsonisms: Prevalence and Affecting Factors. Frontiers in neurology vol. 10 621. 18 Jun. 2019
10. Cassani, E. et al. Use of probiotics for the treatment of constipation in Parkinson’s disease patients. Minerva Gastroenterol Dietol. 2011; Jun;57(2):117-21.
11. Tan, A.H. et al. Probiotics for Parkinson’s disease: Current evidence and future directions. JGH Open, (2021) 5: 414-419.
12. Gras-Miralles, B., Cremonini, F. A critical appraisal of lubiprostone in the treatment of chronic constipation in the elderly, Clin Interv Aging. 2013; 8: 191–200.
13. Gandell D. et al. Treatment of constipation in older people. CMAJ. 2013 May 14;185(8):663-70.
14. Diemel, J.M. et al. NHG – Standaard Obstipatie, Huisarts en Wetenschap, 2010;53(9):484-98
15. Gezondheidsraad. Richtlijn voor de vezelconsumptie. Den Haag: Gezondheidsraad, 2006; publicatie nr 2006/03.
16. Ho, K.S. et al. Stopping or reducing dietary fiber intake reduces constipation and its associated symptoms, World J Gastroenterol, 2012 September 7; 18(33): 4593-4596
17. Kenny, K. A., Skelly, J.M. Dietary fiber for constipation in older adults: a systematic review. Clinical Effectiveness in Nursing, 2001; 5: 120-128
18. Fosnes GS, Lydersen S, Farup PG. Effectiveness of laxatives in elderly–a cross sectional study in nursing homes. BMC Geriatr. 2011 Nov 17;11:76.
19. Lenoir-Wijnkoop I, et al. Probiotics Reduce Health Care Cost and Societal Impact of Flu-Like Respiratory Tract Infections in the USA: An Economic Modeling Study. Front Pharmacol. 2019 Aug 28;10:980
20. Goldenberg JZ. et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database Syst Rev. 2017;12(12):CD006095. 
21. Videlock, E.J., Cremonini, F. Meta-analysis: probiotics in antibiotic-associated diarrhoea. Aliment Pharmacol Ther. 2012 Jun; 35(12):1355-69.
22. McFarland L. Emerging therapies for Clostridium difficile infections. Expert Opin Emerg Drugs. 2011 Sep;16(3):425-39.
23. Hempel S. et al. Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA. 2012 May 9;307(18):1959-69.
24. Hickson M. et al. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial.BMJ 2007;335:80.
25. Stockenhuber, A. et al. Preventing Antibiotic Associated Diarrhoea using a Probiotic Lactobacillus casei Preparation. Gut 2008; 57 (Suppl II) A20
26. Pirker, A. et al. Effects of antibiotic therapy on the gastrointestinal microbiota and the influence of Lactobacillus casei. Food and Agricultural Immunology, 2013; 24(3):315-330.
27. Lee L. et al. Prevention of relapse following Clostridium difficile infection using probiotic Lactobacillus casei Shirota. International Journal of Probiotics & Prebiotics. 2013; 8(4):145-148.

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7. Messaoudi, M., Violle, N., Bisson, J., et al. (2011). Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticusR0052 andBifidobacterium longumR0175) in healthy human volunteers. Gut microbes, 2(4), 256–261.
8. Kato-Kataoka, A., Nishida, K., Takada, M., et al. (2016). Fermented milk containing Lactobacillus casei strain shirota prevents the onset of physical symptoms in medical students under academic examination stress. Beneficial Microbes, 7(2), 153–156.
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1) Diemel, J.M. et al. NHG – Standaard Obstipatie, Huisarts en Wetenschap. 2010;53(9):484-98 
2) Bouterse, M. et al. Huisartsenzorg in cijfers, Obstipatie, Huisarts en Wetenschap. 2010;9:463-463. 
3) Shafe, A.C.E. et alThe LUCK study: Laxative Usage in patients with GP diagnosed Constipation in the UK, within the general population and in pregnancy. An epidemiological study using the General Practice Research Database (GPRD) Therap Adv Gastroenterol. 2011. 4(6): 343–363. 
4) Milliano, I. de, et al. Is a multispecies probiotic mixture effective in constipation during pregnancy? ‘A pilot study’, Nutr J. 2012, 11:80 
5) Bosshard, W. et al. The treatment of chronic constipation in elderly people: an update. Drugs Aging. 2004, 21(14):911-30 
6) Gras-Miralles, B., Cremonini, F. A critical appraisal of lubiprostone in the treatment of chronic constipation in the elderly, Clin Interv Aging. 2013; 8: 191–200
7) Flach J., Koks M., van der Waal M.B., Claassen E., Larsen O.F.A. Economic potential of probiotic supplementation in institutionalized elderly with chronic constipation (2018)  PharmaNutrition,  6  (4) , pp. 198-206. 
8) Rome Foundation, Appendix A, Rome III Diagnostic Criteria for Functional Gastrointestinal Disorders 
9) Kumar, P., Clark, M. (eds.) Clinical Medicine. 2012 8th ed. Edinburgh: Elsevier Saunders 
10) Chmielewska, A., Szajewska, H. Systematic review of randomised controlled trials: Probiotics for functional constipation, World J Gastroenterol. 2010; 16(1): 69–75 
11) Gezondheidsraad. Richtlijn voor de vezelconsumptie. Den Haag: Gezondheidsraad, 2006; publicatie nr 2006/03. ISBN 90-5549-589-1 
12) Ho, K.S. et al. Stopping or reducing dietary fiber intake reduces constipation and its associated symptoms, World J Gastroenterol, 2012; 7; 18(33): 4593-4596 
13) Kenny, K. A., Skelly, J.M. Dietary fiber for constipation in older adults: a systematic review. Clin. Eff Nurs. 2001;5:120-128 
14) Fosnes, G.S. et al. Effectiveness of laxatives in elderly – a cross sectional study in nursing homes. BMC Geriatr. 2011;11.76 
15) Horst, H.E. van der, et al. NHG-Standaard Prikkelbaredarmsyndroom (PDS) (Eerste herziening) Huisarts en Wetenschap. 2012; 55(5):204-9 
16) Koebnick, C. et al. Probiotic beverage containing Lactobacillus casei Shirota improves gastrointestinal symtoms in patients with chronic constipation. Can J Gastroenterol. 2003; 17(11):655-9. 
17) Yang Y.X. et al. Effect of a fermented milk containing Bifidobacterium lactis DN-173101 on Chinese constipated women. World J. Gastroenterol. 2008; 14: 6237-6243 
18) Mollenbrink, M., Bruckschen, E. Treatment of chronic constipation with physiologic Escherichia coli bacteria. Results of a clinical study of the effectiveness and tolerance of  microbiological therapy with the E. coli Nissle 1917 strain (Mutaflor). Med Klin, 1994 (Munich) 89: 587–593 
19) Ouwehand AC. et al. Effectiveness of Multi-strain Versus Single-strain Probiotics: Current Status and Recommendations for the Future, J Clin Gastroenterol. 2018; 52(suppl 1):S35–S40. 
20) Lee B. et al. Attenuation of colitis by Lactobacillus casei BL23 is dependent on the dairy delivery matrix. Appl Environ Microbiol. 2015;81(18):6425-6435  
21) Burgain J. Encapsulation of Lactobacillus rhamnosus GG in microparticles: Influence of casein to whey protein ratio on bacterial survival during digestion. Innovative Food Science & Emerging Technologies. 2013;(19): 233–242 
22) Flach et al. The underexposed role of food matrices in probiotic products: Reviewing the relationship between carrier matrices and product parameters. Crit Rev Food Sci Nutr. 2018;58(15):2570-2584. 
23) Ouwehand AC. A review of dose-responses of probiotics in  human  studies.  Benef ical Microbes. 2017;8(2):143-151.   
24) ISAPP resources ‘What are probiotics?’

1. How mud boosts your immune system Alessia Franco and David Robson – BBC / Family Tree – 11th October 2022 https://www.bbc.com/future/article/20220929-how-outdoor-play-boosts-kids-immune-systems
2. Prebiotics in the Infant Microbiome: The Past, Present, and Future Miqdady M, Al Mistarihi J, Azaz A, Rawat D.. Pediatr Gastroenterol Hepatol Nutr. 2020 Jan;23(1):1-14 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966216
3. Probiotics in Pediatrics. A Review and Practical Guide Depoorter L, Vandenplas Y.. Nutrients. 2021 Jun 24;13(7):2176. doi: 10.3390/nu13072176. PMID: 34202742; PMCID:PMC8308463. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308463/
4. Efficacy of probiotics on digestive disorders and acute respiratory infections: a controlled clinical trial in young Vietnamese children Mai, T.T., Thi Thu, P., Thi Hang, H. et al.. Eur J Clin Nutr 75, 513–520 (2021) https://www.nature.com/articles/s41430-020-00754-9
5. Role of probiotic in preventing acute diarrhoea in children: a community-based, randomized, double-blind placebo-controlled field trial in an urban slum Sur D, et al. Epidemiol Infect. 2011 Jun;139(6):919-26.doi:10.1017/ S0950268810001780. Epub 2010 Jul 30. PMID: 20670468. https://pubmed.ncbi.nlm.nih.gov/20670468/
6. Probiotics for the prevention of pediatric antibiotic associated diarrhea Qin Guo, Joshua Z Goldenberg, Claire Humphrey, Regina El Dib, Bradley C Johnston https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004827.pub5/full
7. Probiotic and synbiotic safety in infants under two years of age van den Nieuwboer M, Claassen E, Morelli L, Guarner F, Brummer RJ.. Benef Microbes. 2014 Mar;5(1):45-60. https://pubmed.ncbi.nlm.nih.gov/24463207/
8. Safety of probiotics and synbiotics in children under 18 years of age. van den Nieuwboer M, Brummer RJ, Guarner F, Morelli L, Cabana M, Claassen E. Benef Microbes. 2015;6(5):615-30. https://pubmed.ncbi.nlm.nih.gov/25809217/
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